Publications
2024
Deep Transcriptomics Reveals Cell-Specific Isoforms of Pan-Neuronal Genes. Zachery Wolfe, David Liska, Adam Norris. bioRxiv. 2024 May 20. doi: 10.1101/2024.05.16.594572.
Access the VISTA-SPLICE visualization here
Conserved role for spliceosomal component PRPF40A in microexon splicing. Bikash Choudhary, Adam Norris. RNA. 2024. Oct 10. doi: 10.1261/rna.080142.124.
A pair of RNA binding proteins inhibit ion transporter expression to maintain lifespan. Rebekah Napier-Jameson, Olivia Marx, Adam Norris. Genetics. 2024 Feb 7. doi: 10.1093/genetics/iyad212.
2023
VISTA: Visualizing the Spatial Transcriptome of the C. elegans Nervous System. David Liska, Zachery Wolfe, Adam Norris. Bioinformatics Advances. 2023 Sep 27. doi: 10.1093/bioadv/vbad127.
Access the VISTA online visualization here
TDP-1 and FUST-1 co-inhibit exon inclusion and control fertility together with transcriptional regulation. Morgan Taylor, Olivia Marx, Adam Norris. Nucleic Acids Research. 2023 Aug 17. doi: 10.1093/nar/gkad665.
A primary microcephaly-associated sas-6 mutation perturbs centrosome duplication and ciliogenesis in Caenorhabditis elegans. Bergwell, M., Smith, A., Smith, E., Duran, R., Haastrup, E., Napier-Jameson, R., Dierlam, C., Seidel, R., Potter, W., Norris, A, Iyer, J. Genetics. 2023 Jun 4. doi: 10.1093/genetics/iyad105.
2022
A conserved role for stomatin domain genes in olfactory behavior. Xiaoyu Liang*, Morgan Taylor*, Rebekah Napier-Jameson, Canyon Calovich-Benne, Adam Norris. bioRxiv 2022 Sep 27. eNeuro. 2023 Mar 1. doi: 10.1523/ENEURO.0457-22.2023.
Sensory neuron transcriptomes reveal complex neuron-specific function and regulation of mec-2/Stomatin splicing. Xiaoyu Liang*, Canyon Calovich-Benne*, Adam Norris. Nucleic Acids Research. 2022 Mar 21. 50(5): 2401-2406. doi: 10.1093/nar/gkab1134.
Selected by Nucleic Acids Research as a Breakthrough Article
2021
A new gene on C. elegans chromosome V. Anusha Iyengar, Stavros Diamantakis, Adam Norris. microPublication. 2021 Nov 3. 10:17912. doi: 10.17912/micropub.biology.000496.
Highlighted on the WormBase News Homepage
Spliceosomal Component PRP-40 is a Central Regulator of Microexon Splicing. Bikash Choudhary, Olivia Marx, Adam Norris. Cell Reports. 2021 Aug 3. 36(5): 109464. doi: 10.1016/j.celrep.2021.109464
2019
Splicing in a single neuron is coordinately controlled by RNA binding proteins and transcription factors. Morgan Thompson, Ryan Bixby, Robert Dalton, Alexa Vandenburg, John Calarco, Adam Norris. eLife. 2019 Jul 19;8. pii: e46726. doi: 10.7554/eLife.46726.
Profiled in Science Daily
2018
Calarco, JA, Norris AD. Synthetic Genetic Interaction (CRISPR-SGI) Profiling in Caenorhabditis elegans. Calarco, JA, Norris AD. Bio-protocol. 2018 8(5): e2756.
2017
CRISPR-mediated genetic interaction profiling identifies RNA binding proteins controlling metazoan fitness. Norris AD, Gracida X, Calarco J. eLife. 2017 Jul 18;6. pii: e28129
2016
Regulation of Tissue-Specific Alternative Splicing: C. elegans as a Model System. Gracida X, Norris AD, Calarco JA. Adv Exp Med Biol. 2016;907:229-61.
2015
Efficient Genome Editing in Caenorhabditis elegans with a Toolkit of Dual-Marker Selection Cassettes. Norris AD, Kim HM, Colaiácovo MP, Calarco JA. Genetics. 2015 Oct;201(2):449-58.
2014
A pair of RNA-binding proteins controls networks of splicing events contributing to specialization of neural cell types. Norris AD, Gao S, Norris ML, Ray D, Ramani AK, Fraser AG, Morris Q, Hughes TR, Zhen M, Calarco JA. Molecular Cell. 2014 Jun 19;54(6):946-59.
Profiled in Molecular Cell: Networking in an alternative splicing world
The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP. Norris AD, Sundararajan L, Morgan DE, Roberts ZJ, Lundquist EA. Development. 2014 Nov;141(22):4395-405.
<2014
Emerging Roles of Alternative Pre-mRNA Splicing Regulation in Neuronal Development and Function. Norris AD, Calarco JA. Front Neurosci. 2012 Aug 21;6:122.
UNC-6/netrin and its receptors UNC-5 and UNC-40/DCC modulate growth cone protrusion in vivo in C. elegans. Norris AD, Lundquist EA. Development. 2011 Oct;138(20):4433-42.
The Arp2/3 complex, UNC-115/abLIM, and UNC-34/Enabled regulate axon guidance and growth cone filopodia formation in Caenorhabditis elegans. Norris AD, Dyer JO, Lundquist EA. Neural Development 2009 Oct 2;4:38.